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Spatio-temporal cell cycle phase analysis using level sets and fast marching methods.

Abstract:

Enabled by novel molecular markers, fluorescence microscopy enables the monitoring of multiple cellular functions using live cell assays. Automated image analysis is necessary to monitor such model systems in a high-throughput and high-content environment. Here, we demonstrate the ability to simultaneously track cell cycle phase and cell motion at the single cell level. Using a recently introduced cell cycle marker, we present a set of image analysis tools for automated cell phase analysis of...

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Publisher copy:
10.1016/j.media.2008.06.018

Authors


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Institution:
University of Oxford
Department:
Oxford, MPLS, Clinical Medicine, Biomedical Research Centre
Role:
Author
Journal:
Medical image analysis
Volume:
13
Issue:
1
Pages:
143-155
Publication date:
2009-02-05
DOI:
EISSN:
1361-8423
ISSN:
1361-8415
URN:
uuid:79d1f870-fb6e-4bd4-a5ce-640c67c35fe8
Source identifiers:
426715
Local pid:
pubs:426715

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