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Positive and negative selection on mammalian Y chromosomes.

Abstract:

Y chromosomes are genetically degenerate in most organisms studied. The loss of genes from Y chromosomes is thought to be due to the inefficiency of purifying selection in nonrecombining regions, which leads to the accumulation of deleterious mutations via the processes of hitchhiking, background selection, and Muller's ratchet. As the severity of these processes depends on the number of functional genes linked together on the nonrecombining Y, it is not clear whether these processes are stil...

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Publication status:
Published

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Publisher copy:
10.1093/molbev/msi128

Authors


Gerrard, DT More by this author
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Institution:
University of Oxford
Department:
Oxford, MPLS, Plant Sciences
Journal:
Molecular biology and evolution
Volume:
22
Issue:
6
Pages:
1423-1432
Publication date:
2005-06-05
DOI:
EISSN:
1537-1719
ISSN:
0737-4038
URN:
uuid:796a8945-1fdd-4901-9a95-b72fa008333f
Source identifiers:
49192
Local pid:
pubs:49192

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