Further evidence for a parent-of-origin effect at the NOP9 locus on language-related phenotypes
Background: Specific Language Impairment (SLI) is a common neurodevelopmental disorder, observed in 5-10% of children. Family and twin studies suggest a strong genetic component, but relatively few candidate genes have been reported to date. A recent genome-wide association study (GWAS) described the first statistically significant association specifically for a SLI cohort between a missense variant (rs4280164) in the NOP9 gene and language-related phenotypes under a parent-of-origin model. R...Expand abstract
- Publication status:
- Peer review status:
- Peer reviewed
- Publisher's version
- Copyright holder:
- Pettigrew et al.
- Copyright date:
- © 2016 The Author(s). Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License.
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