Improving target delineation on 4-dimensional CT scans in stage I NSCLC using a deformable registration tool.

Journal article

INTRODUCTION: Correct target definition is crucial in stereotactic radiotherapy for lung tumors. We evaluated use of deformable registration (DR) for target contouring on 4-dimensional (4D) CT scans. MATERIALS AND METHODS: Three clinicians contoured gross tumor volume (GTV) in an end-inspiration phase of 4DCT of 6 patients on two occasions. Two clinicians contoured GTVs in all phases of 4DCT and on maximum intensity projections (MIP). The initial GTV was auto-propagated to 9 other phases usi...

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Authors: van Dam, I; de Koste, v; Hanna, G; Muirhead, R; Slotman, B

• Publication status: Published
• Journal: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
• Volume: 96
• Issue: 1
• Pages: 67-72
• Publication date: 2010-07-01
• DOI: 10.1016/j.radonc.2010.05.003
• EISSN: 1879-0887
• ISSN: 0167-8140
• Language: English
• Keywords: Four-Dimensional Computed Tomography; Neoplasm Staging; Sampling Studies; Radiosurgery; Humans; Male; Observer Variation; Female; Lung Neoplasms; Carcinoma, Non-Small-Cell Lung; Radiotherapy Planning, Computer-Assisted