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A note on estimating the Cox-Snell R2 from a reported C statistic (AUROC) to inform sample size calculations for developing a prediction model with a binary outcome

Abstract:

In 2019 we published a pair of articles in Statistics in Medicine that describe how to calculate the minimum sample size for developing a multivariable prediction model with a continuous outcome, or with a binary or time‐to‐event outcome. As for any sample size calculation, the approach requires the user to specify anticipated values for key parameters. In particular, for a prediction model with a binary outcome, the outcome proportion and a conservative estimate for the...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1002/sim.8806

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Role:
Author
ORCID:
0000-0001-8699-0735
More by this author
Role:
Author
ORCID:
0000-0003-1613-7450
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Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Sub department:
Botnar Research Centre
Role:
Author
ORCID:
0000-0002-2772-2316
Publisher:
Wiley
Journal:
Statistics in Medicine More from this journal
Volume:
40
Issue:
4
Pages:
859-864
Place of publication:
England
Publication date:
2020-12-07
Acceptance date:
2020-10-23
DOI:
EISSN:
1097-0258
ISSN:
0277-6715
Pmid:
33283904
Language:
English
Keywords:
Pubs id:
1148429
Local pid:
pubs:1148429
Deposit date:
2020-12-21

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