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Journal article

Randomized comparison of the efficacies and tolerabilities of three artemisinin-based combination treatments for children with acute Plasmodium falciparum malaria in the Democratic Republic of the Congo.

Abstract:

An open-label, randomized controlled trial was carried out in 2011-2012 in the Democratic Republic of the Congo to test the efficacy, safety, and tolerability of the artemisinin-based combination treatments dihydroartemisinin-piperaquine, amodiaquine-artesunate, and artemether-lumefantrine. Six hundred eighty-four children aged 3 to 59 months with uncomplicated Plasmodium falciparum malaria were randomly allocated to each study arm. Children were hospitalized for 3 days, given supervised trea...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1128/aac.02682-14

Authors


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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Thailand/Laos MOP
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Thailand/Laos MOP
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Thailand/Laos MOP
Role:
Author
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Wellcome Trust More from this funder
Publisher:
American Society for Microbiology Publisher's website
Journal:
Antimicrobial agents and chemotherapy Journal website
Volume:
58
Issue:
9
Pages:
5528-5536
Publication date:
2014-09-05
DOI:
EISSN:
1098-6596
ISSN:
0066-4804
URN:
uuid:785224d6-872b-450f-81bd-dedd1271c743
Source identifiers:
475820
Local pid:
pubs:475820
Language:
English

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