Acute vasospasm following transcallosal resection of a xanthogranulomatous colloid cyst of the 3rd ventricle.

Journal article

We present the first case of a 57 year old man who developed severe, acute vasospasm following transcallosal resection of an unusual, xanthogranulomatous colloid cyst. The 16 year history of growth of this cyst may have resulted in its unusual pathology, and the subsequent vasospastic reaction to its excision. We discuss the potential pathological relationship between the inflammatory nature of the cyst, chemical meningitis and vasospasm, and what this implies about vasospasm in general. The severe, life-threatening vasospasm affected all four major vessels and required aggressive management by endovascular injection of nimodipine and angioplasty, with good recovery. The case illustrates a previously undescribed sequel of surgery for this condition, demonstrates an effective treatment and offers possible insights into the pathogenesis of vasospasm.

Authors: Webb, A; Gillies, M; Cadoux-Hudson, T

• Publication status: Published
• Journal: Clinical neurology and neurosurgery
• Volume: 112
• Issue: 6
• Pages: 512-515
• Publication date: 2010-07-01
• DOI: 10.1016/j.clineuro.2010.03.009
• EISSN: 1872-6968
• ISSN: 0303-8467
• Language: English
• Keywords: Angioplasty; Meningitis, Aseptic; Calcium Channel Blockers; Central Nervous System Cysts; Tomography, X-Ray Computed; Granuloma; Corpus Callosum; Magnetic Resonance Imaging; Magnetic Resonance Angiography; Male; Nimodipine; Neurosurgical Procedures; Third Ventricle; Humans; Cerebral Angiography; Mental Disorders; Postoperative Complications; Diabetes Mellitus, Type 2; Cerebral Ventricle Neoplasms; Middle Aged; Vasospasm, Intracranial