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MR1: an unconventional twist in the tail

Abstract:
MR1 is a conserved molecule that binds microbial vitamin B metabolites and presents them to unconventional T cells. Lim and colleagues (2022. J. Cell Biol.https://doi.org/10.1083/jcb.202110125) uncover the role of AP2 in ensuring MR1 surface presentation, which relies on an atypical motif within the MR1 cytoplasmic tail.
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1083/jcb.202211016

Authors

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
NDM Experimental Medicine
Oxford college:
Green Templeton College
Role:
Author
ORCID:
0000-0003-4307-9161


Publisher:
Rockefeller University Press
Journal:
Journal of Cell Biology More from this journal
Volume:
221
Issue:
12
Article number:
e202211016
Place of publication:
United States
Publication date:
2022-11-14
DOI:
EISSN:
1540-8140
ISSN:
0021-9525
Pmid:
36374222


Language:
English
Keywords:
Subtype:
Comment
Pubs id:
1305882
Local pid:
pubs:1305882
Deposit date:
2023-10-17
ARK identifier:

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