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ASL-BIDS, the brain imaging data structure extension for arterial spin labeling

Abstract:
Arterial spin labeling (ASL) is a non-invasive MRI technique that allows for quantitative measurement of cerebral perfusion. Incomplete or inaccurate reporting of acquisition parameters complicates quantification, analysis, and sharing of ASL data, particularly for studies across multiple sites, platforms, and ASL methods. There is a strong need for standardization of ASL data storage, including acquisition metadata. Recently, ASL-BIDS, the BIDS extension for ASL, was developed and released in BIDS 1.5.0. This manuscript provides an overview of the development and design choices of this first ASL-BIDS extension, which is mainly aimed at clinical ASL applications. Discussed are the structure of the ASL data, focussing on storage order of the ASL time series and implementation of calibration approaches, unit scaling, ASL-related BIDS fields, and storage of the labeling plane information. Additionally, an overview of ASL-BIDS compatible conversion and ASL analysis software and ASL example datasets in BIDS format is provided. We anticipate that large-scale adoption of ASL-BIDS will improve the reproducibility of ASL research.
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1038/s41597-022-01615-9

Authors

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Role:
Author
ORCID:
0000-0001-8546-0134
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Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Role:
Author
ORCID:
0000-0001-8258-0659
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Role:
Author
ORCID:
0000-0003-1491-1641


Publisher:
Springer Nature
Journal:
Scientific Data More from this journal
Volume:
9
Issue:
1
Article number:
543
Place of publication:
England
Publication date:
2022-09-06
Acceptance date:
2022-08-05
DOI:
EISSN:
2052-4463
ISSN:
2052-4463
Pmid:
36068231


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