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Thesis

Molecular dynamics simulations of lipase-surface interactions

Abstract:

Lipases are enzymes that play fundamental roles in fat digestion and metabolism, and function at the interface formed between hydrophobic molecules and the surrounding aqueous environment. These interfacial interactions are thought to induce conformational changes in a "lid" region of the lipase, leading to a dramatic increase in activity. This thesis aims to provide insight into the interactions that govern lipase association with interfaces of di erent structural characteristics, and the...

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Division:
MSD
Department:
Biochemistry
Role:
Author

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Role:
Supervisor
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
Language:
English
Keywords:
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UUID:
uuid:7765c334-7c02-4190-a4b2-99ad315cfe52
Deposit date:
2018-04-12

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