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An altered endometrial CD8 Tissue Resident memory T cell population in recurrent miscarriage

Abstract:

When trying to conceive 1% of couples have recurrent miscarriages, defined as three or more consecutive pregnancy losses. This is not accounted for by the known incidence of chromosomal abnormality in miscarriage, and it has been suggested that there is an immunological aetiology. The endometrial mucosa is populated by a variety of immune cells which in addition to providing host pathogen immunity must facilitate pregnancy. Here we characterise the endometrial CD8-T cell population durin...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1038/srep41335

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Department:
Oxford, MSD, Obstetrics & Gynaecology
Role:
Author
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Department:
Oxford, MSD, Obstetrics & Gynaecology
Role:
Author
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Publisher:
Nature Publishing Group Publisher's website
Journal:
Scientific Reports Journal website
Volume:
7
Pages:
Article: 41335
Publication date:
2017-01-01
Acceptance date:
2016-12-16
DOI:
ISSN:
2045-2322
Pubs id:
pubs:667979
URN:
uri:7686e35d-f00c-441e-8b50-fab39b7f3c98
UUID:
uuid:7686e35d-f00c-441e-8b50-fab39b7f3c98
Local pid:
pubs:667979

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