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An altered endometrial CD8 Tissue Resident memory T cell population in recurrent miscarriage

Abstract:

When trying to conceive 1% of couples have recurrent miscarriages, defined as three or more consecutive pregnancy losses. This is not accounted for by the known incidence of chromosomal abnormality in miscarriage, and it has been suggested that there is an immunological aetiology. The endometrial mucosa is populated by a variety of immune cells which in addition to providing host pathogen immunity must facilitate pregnancy. Here we characterise the endometrial CD8-T cell population durin...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1038/srep41335

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Institution:
University of Oxford
Division:
MSD
Department:
Women's and Reproductive Health
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Women's and Reproductive Health
Role:
Author
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Publisher:
Nature Publishing Group Publisher's website
Journal:
Scientific Reports Journal website
Volume:
7
Article number:
41335
Publication date:
2017-01-01
Acceptance date:
2016-12-16
DOI:
ISSN:
2045-2322
Source identifiers:
667979
Pubs id:
pubs:667979
UUID:
uuid:7686e35d-f00c-441e-8b50-fab39b7f3c98
Local pid:
pubs:667979
Deposit date:
2017-01-04

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