- Abstract:
-
The Fanconi anemia (FA) pathway plays a central role in the repair of DNA interstrand crosslinks (ICLs) and regulates cellular responses to replication stress. Homologous recombination (HR), the error-free pathway for double-strand break (DSB) repair, is required during physiological cell cycle progression for the repair of replication-associated DNA damage and protection of stalled replication forks. Substantial crosstalk between the two pathways has recently been unravelled, in that key HR ...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Accepted manuscript
- Files:
-
-
(pdf, 464.5KB)
-
- Publisher copy:
- 10.15252/embj.201693860
-
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- Publisher:
- EMBO Press Publisher's website
- Journal:
- The EMBO journal Journal website
- Volume:
- 35
- Issue:
- 9
- Pages:
- 909-923
- Publication date:
- 2016-04-01
- Acceptance date:
- 2016-03-08
- DOI:
- EISSN:
-
1460-2075
- ISSN:
-
0261-4189
- URN:
-
uuid:76850dc9-939b-462d-87a0-bf83d497d2ec
- Source identifiers:
-
614041
- Local pid:
- pubs:614041
- Paper number:
- 9
- Language:
- English
- Keywords:
- Copyright holder:
- Johanna Michl et al.
- Copyright date:
- 2016
- Notes:
-
This is an open access article under the terms of the Creative Commons Attribution 4.0
License (https://creativecommons.org/licenses/by/4.0), which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
Journal article
Interplay between Fanconi anemia and homologous recombination pathways in genome integrity
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