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Journal article

Effects of aspirin for primary prevention in persons with diabetes mellitus

Abstract:

Background Diabetes mellitus is associated with an increased risk of cardiovascular events. Aspirin use reduces the risk of occlusive vascular events but increases the risk of bleeding; the balance of benefits and hazards for the prevention of first cardiovascular events in patients with diabetes is unclear. Methods We randomly assigned adults who had diabetes but no evident cardiovascular disease to receive aspirin at a dose of 100 mg daily or matching placebo. The primary efficacy outcome w...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's Version

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Publisher copy:
10.1056/nejmoa1804988

Authors


More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Nuffield Department of Population Health
Subgroup:
Clinical Trial Service Unit
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Nuffield Department of Population Health
Subgroup:
Clinical Trial Service Unit
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Nuffield Department of Population Health
Subgroup:
Clinical Trial Service Unit
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Nuffield Department of Population Health
Subgroup:
Clinical Trial Service Unit
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Nuffield Department of Population Health
Subgroup:
Clinical Trial Service Unit
Role:
Author
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Publisher:
Massachusetts Medical Society Publisher's website
Journal:
New England Journal of Medicine Journal website
Volume:
379
Pages:
1529-1539
Publication date:
2018-10-18
Acceptance date:
2018-08-06
DOI:
EISSN:
1533-4406
ISSN:
0028-4793
Pubs id:
pubs:920636
URN:
uri:766dc97c-90ef-49a1-8dc5-9c2c00734865
UUID:
uuid:766dc97c-90ef-49a1-8dc5-9c2c00734865
Local pid:
pubs:920636

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