- Abstract:
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Background Diabetes mellitus is associated with an increased risk of cardiovascular events. Aspirin use reduces the risk of occlusive vascular events but increases the risk of bleeding; the balance of benefits and hazards for the prevention of first cardiovascular events in patients with diabetes is unclear. Methods We randomly assigned adults who had diabetes but no evident cardiovascular disease to receive aspirin at a dose of 100 mg daily or matching placebo. The primary efficacy outcome w...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Publisher's Version
- Files:
-
-
(pdf, 475.1KB)
-
- Publisher copy:
- 10.1056/nejmoa1804988
-
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- Publisher:
- Massachusetts Medical Society Publisher's website
- Journal:
- New England Journal of Medicine Journal website
- Volume:
- 379
- Pages:
- 1529-1539
- Publication date:
- 2018-10-18
- Acceptance date:
- 2018-08-06
- DOI:
- EISSN:
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1533-4406
- ISSN:
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0028-4793
- Pubs id:
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pubs:920636
- URN:
-
uri:766dc97c-90ef-49a1-8dc5-9c2c00734865
- UUID:
-
uuid:766dc97c-90ef-49a1-8dc5-9c2c00734865
- Local pid:
- pubs:920636
- Language:
- English
- Keywords:
- Copyright holder:
- Massachusetts Medical Society
- Copyright date:
- 2018
- Notes:
- © 2018 Massachusetts Medical Society. This is the publisher's version of the article. The final version is available online from Massachusetts Medical Society at: 10.1056/NEJMoa1804988
Journal article
Effects of aspirin for primary prevention in persons with diabetes mellitus
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