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5-HT modulation by acute tryptophan depletion of human instrumental contingency judgements.

Abstract:

INTRODUCTION: The concept of 'depressive realism', that depression leads to more accurate perception of causal control, has been influential in the field of depression research, but remains controversial. Recent work testing contingency learning has suggested that contextual processing might determine realism-like effects. Serotonin (5-hydroxytryptamine, (5-HT)), which is implicated in the pathophysiology of depression, might also influence contextual processing. Using acute tryptophan deplet...

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Publication status:
Published

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Publisher copy:
10.1007/s00213-010-1934-4

Authors


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Institution:
University of Oxford
Department:
Oxford, MSD, Experimental Psychology
Msetfi, RM More by this author
Murphy, RA More by this author
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Journal:
Psychopharmacology
Volume:
213
Issue:
2-3
Pages:
615-623
Publication date:
2011-02-05
DOI:
EISSN:
1432-2072
ISSN:
0033-3158
URN:
uuid:76686783-bd85-4879-8a8e-e3e655420ae2
Source identifiers:
186164
Local pid:
pubs:186164

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