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Adiponectin: From obesity to cardiovascular disease: Etiology and Pathophysiology

Abstract:

Adiponectin is an adipokine whose biosynthesis is deranged in obesity and diabetes mellitus, predisposing to atherosclerosis. Evidence suggests that adiponectin has anti-atherogenic properties by improving endothelial function and having anti-inflammatory effects in the vascular wall. In addition, adiponectin modifies vascular intracellular redox signalling and exerts indirect antioxidant effects on human myocardium. However, its clinical role in cardiovascular disease is obscure. Adiponectin...

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Authors


Antoniades, C More by this author
Antonopoulos, AS More by this author
Tousoulis, D More by this author
Stefanadis, C More by this author
Journal:
Obesity Reviews
Volume:
10
Issue:
3
Pages:
269-279
Publication date:
2009-05-05
DOI:
EISSN:
1467-789X
ISSN:
1467-7881
URN:
uuid:76318f36-0357-4b17-bbfd-a93b42d221e2
Source identifiers:
223334
Local pid:
pubs:223334

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