Single protein pores containing molecular adapters at high temperatures.

Journal article

Bearing the heat: Current has been measured from individual protein pores at temperatures approaching 100°C. The molecular adapter β-cyclodextrin (red) remains bound to the α-hemolysin pore at high temperatures and retains the ability to bind guest molecules (black). Recording current at high temperatures is likely to be important for the study of single-molecule chemistry and in the development of stochastic sensors. © 2005 Wiley-VCH Verlag GmbH and Co. KGaA, Weinheim.

Authors: Kang, X; Gu, L; Cheley, S; Bayley, H

• Publication status: Published
• Journal: Angewandte Chemie (International ed. in English)
• Volume: 44
• Issue: 10
• Pages: 1495-1499
• Publication date: 2005-02-01
• DOI: 10.1002/anie.200461885
• EISSN: 1521-3773
• ISSN: 1433-7851
• Language: English
• Keywords: Hot Temperature; Sensitivity and Specificity; Proteins