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Predicting pathological response of esophageal cancer to neoadjuvant chemotherapy: the implications of metabolic nodal response for personalised therapy

Abstract:

INTRODUCTION
Only a minority of esophageal cancers demonstrates a pathological tumor response (pTR) to neoadjuvant chemotherapy (NAC). 18F-fluorodeoxyglucose (FDG) positron emission tomography-computed tomography (PET-CT) is often used for restaging after NAC and to assess response. Increasingly, it is used during therapy to identify unresponsive tumors and predict pTR , using avidity of the primary tumor alone. However, definitions of such metabolic tumor response (mTR) vary. We aimed t...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Accepted manuscript

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Publisher copy:
10.2967/jnumed.116.176313

Authors


Findlay, JM More by this author
Bradley, KM More by this author
Mun Wang, L More by this author
Franklin, JM More by this author
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Publisher:
Society of Nuclear Medicine Publisher's website
Journal:
Journal of Nuclear Medicine Journal website
Publication date:
2016-09-05
Acceptance date:
2016-07-13
DOI:
EISSN:
2159-662X
ISSN:
0161-5505
URN:
uuid:75c0b8ec-7564-41be-a588-092e96e89593
Source identifiers:
634139
Local pid:
pubs:634139

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