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Journal article

Interactions between genome-wide significant genetic variants and circulating concentrations of insulin-like growth factor 1, sex hormones, and binding proteins in relation to prostate cancer risk in the National Cancer Institute Breast and Prostate Cancer Cohort Consortium.

Abstract:

Genome-wide association studies (GWAS) have identified many single nucleotide polymorphisms (SNPs) associated with prostate cancer risk. There is limited information on the mechanistic basis of these associations, particularly about whether they interact with circulating concentrations of growth factors and sex hormones, which may be important in prostate cancer etiology. Using conditional logistic regression, the authors compared per-allele odds ratios for prostate cancer for 39 GWAS-identif...

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Publication status:
Published

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Publisher copy:
10.1093/aje/kwr423

Authors


Tsilidis, KK More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, Cancer Epidemiology Unit
Appleby, PN More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, Cancer Epidemiology Unit
Lindstrom, S More by this author
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Journal:
American journal of epidemiology
Volume:
175
Issue:
9
Pages:
926-935
Publication date:
2012-05-05
DOI:
EISSN:
1476-6256
ISSN:
0002-9262
URN:
uuid:7563964d-7165-4403-b73d-3cdd9b743722
Source identifiers:
333966
Local pid:
pubs:333966

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