Journal article
Differential impact of behavioral, social, and emotional apathy on Parkinson's disease
- Abstract:
- Apathy is highly prevalent in Parkinson's disease. New findings suggest the syndrome is multifaceted. Here, we investigate whether all aspects of apathy are equally affected in Parkinson's disease and whether different dimensions of apathy were associated with depression and anhedonia. On the Apathy Motivation Index, while behavioral apathy and social apathy were elevated, emotional motivation was relatively preserved in Parkinson's disease, although a few patients did show impaired emotional sensitivity. Behavioral and social, but not emotional, apathy was associated with depression and anhedonia. These findings suggest aspects of motivation can be selectively impaired in Parkinson's disease and may have implications for guiding treatment.
- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Preview, Version of record, pdf, 223.1KB, Terms of use)
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- Publisher copy:
- 10.1002/acn3.626
Authors
+ Medical Research Council
More from this funder
- Funding agency for:
- Lockwood, P
- Grant:
- MR/P014097/1
- Publisher:
- Wiley
- Journal:
- Annals of Clinical and Translational Neurology More from this journal
- Volume:
- 5
- Issue:
- 10
- Pages:
- 1286-1291
- Publication date:
- 2018-08-14
- Acceptance date:
- 2018-07-06
- DOI:
- EISSN:
-
2328-9503
- Pubs id:
-
pubs:911576
- UUID:
-
uuid:754f6f1b-9375-4160-b56d-f7aab40643b7
- Local pid:
-
pubs:911576
- Source identifiers:
-
911576
- Deposit date:
-
2018-08-31
Terms of use
- Copyright holder:
- Ang et al
- Copyright date:
- 2018
- Notes:
- © 2018 The Authors. Annals of Clinical and Translational Neurology published by Wiley Periodicals, Inc on behalf of American Neurological Association. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
- Licence:
- CC Attribution (CC BY)
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