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Journal article

Assessment of the upper motor neuron in amyotrophic lateral sclerosis

Abstract:

Clinical signs of upper motor neuron (UMN) involvement are an important component in supporting the diagnosis of amyotrophic lateral sclerosis (ALS), but are often not easily appreciated in a limb that is concurrently affected by muscle wasting and lower motor neuron degeneration, particularly in the early symptomatic stages of ALS. Whilst recent criteria have been proposed to facilitate improved detection of lower motor neuron impairment through electrophysiological features that have improv...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Accepted manuscript

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Publisher copy:
10.1016/j.clinph.2016.04.025

Authors


Grosskreutz, J More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neurosciences
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University of Sydney More from this funder
Publisher:
Elsevier Publisher's website
Journal:
Clinical Neurophysiology Journal website
Volume:
127
Issue:
7
Pages:
2643–2660
Publication date:
2016-04-05
DOI:
ISSN:
1872-8952
URN:
uuid:74fdc1bb-d6ce-4e3d-b7b1-40c947484d5f
Source identifiers:
618273
Local pid:
pubs:618273

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