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Journal article : Review

Antifibrinolytics (lysine analogues) for the prevention of bleeding in people with haematological disorders

Abstract:
Rationale

People with haematological disorders are frequently at risk of severe or life‐threatening bleeding as a result of thrombocytopenia (reduced platelet count). This is despite the routine use of prophylactic platelet transfusions to prevent bleeding once the platelet count falls below a certain threshold. Platelet transfusions are not without risk and adverse events may be life‐threatening. A possible adjunct to prophylactic platelet transfusions is the use of anti...

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Publication status:
Published

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Publisher copy:
10.1002/14651858.cd009733.pub4

Authors

More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Radcliffe Department of Medicine
Sub department:
RDM-Nuffield Division of Clinical Laboratory Sciences
Role:
Author
ORCID:
No
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Radcliffe Department of Medicine
Sub department:
RDM-Nuffield Division of Clinical Laboratory Sciences
Role:
Author
ORCID:
0000-0003-4309-9162
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Radcliffe Department of Medicine
Sub department:
RDM-Nuffield Division of Clinical Laboratory Sciences
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Radcliffe Department of Medicine
Sub department:
RDM-Nuffield Division of Clinical Laboratory Sciences
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Radcliffe Department of Medicine
Role:
Author
ORCID:
0000-0001-6955-7497


Publisher:
Cochrane Collaboration
Journal:
Cochrane Database of Systematic Reviews More from this journal
Volume:
2
Issue:
2
Article number:
CD009733
Place of publication:
England
Publication date:
2026-02-11
DOI:
EISSN:
1469-493X
Pmid:
41670018


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