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Journal article

Control of sexual differentiation and behavior by the doublesex gene in Drosophila melanogaster.

Abstract:

Doublesex proteins, which are part of the structurally and functionally conserved Dmrt gene family, are important for sex determination throughout the animal kingdom. We inserted Gal4 into the doublesex (dsx) locus of Drosophila melanogaster, allowing us to visualize and manipulate cells expressing dsx in various tissues. In the nervous system, we detected differences between the sexes in dsx-positive neuronal numbers, axonal projections and synaptic density. We found that dsx was required fo...

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Publication status:
Published

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Publisher copy:
10.1038/nn.2515

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Institution:
University of Oxford
Department:
Oxford, MSD, Physiology Anatomy and Genetics
Role:
Author
Journal:
Nature neuroscience
Volume:
13
Issue:
4
Pages:
458-466
Publication date:
2010-04-05
DOI:
EISSN:
1546-1726
ISSN:
1097-6256
URN:
uuid:74cb1c25-f98c-4ad6-8800-253db7a9433c
Source identifiers:
114777
Local pid:
pubs:114777

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