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Obesity and metabolic disease: is adipose tissue the culprit?

Abstract:

Obesity is a risk factor for the development of type 2 diabetes and CVD. Is adipose tissue the culprit in the relationship between obesity and metabolic disease? It is certainly possible to argue that adipose tissue function is disturbed in obesity in such a way that adverse consequences may follow. For instance, lipolysis is down regulated, the sensitivity of lipolysis to insulin is reduced and there are disturbances in the regulation of adipose tissue blood flow. However, when examined crit...

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Publication status:
Published

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Publisher copy:
10.1079/pns2004403

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Institution:
University of Oxford
Department:
Oxford, MSD, RDM, OCDEM
Volume:
64
Issue:
1
Pages:
7-13
Publication date:
2005-02-05
DOI:
EISSN:
1475-2719
ISSN:
0029-6651
URN:
uuid:73e2bf4e-e5ea-4061-a9f7-6b5b459e8bfe
Source identifiers:
29524
Local pid:
pubs:29524

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