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Journal article

Multivalent protein binding and precipitation by self-assembling molecules on a DNA pentaplex scaffold.

Abstract:
A supramolecular assembly containing an isoguanosine pentaplex with both a "protein-binding" face and a "reporter" face has been generated. When phosphocholine is appended to the protein-binding face this supramolecular assembly binds multivalently to the pentameric human C-reactive protein, a biomolecule implicated in inflammation and heart disease.
Publication status:
Published

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Publisher copy:
10.1021/ja809219p

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Journal:
Journal of the American Chemical Society More from this journal
Volume:
131
Issue:
14
Pages:
5020-5021
Publication date:
2009-04-01
DOI:
EISSN:
1520-5126
ISSN:
0002-7863


Language:
English
Keywords:
Pubs id:
pubs:117474
UUID:
uuid:73e208b4-eb28-4e79-bb99-8b0b08b117e6
Local pid:
pubs:117474
Source identifiers:
117474
Deposit date:
2012-12-19

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