Journal article
Multivalent protein binding and precipitation by self-assembling molecules on a DNA pentaplex scaffold.
- Abstract:
- A supramolecular assembly containing an isoguanosine pentaplex with both a "protein-binding" face and a "reporter" face has been generated. When phosphocholine is appended to the protein-binding face this supramolecular assembly binds multivalently to the pentameric human C-reactive protein, a biomolecule implicated in inflammation and heart disease.
- Publication status:
- Published
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Authors
- Journal:
- Journal of the American Chemical Society More from this journal
- Volume:
- 131
- Issue:
- 14
- Pages:
- 5020-5021
- Publication date:
- 2009-04-01
- DOI:
- EISSN:
-
1520-5126
- ISSN:
-
0002-7863
- Language:
-
English
- Keywords:
- Pubs id:
-
pubs:117474
- UUID:
-
uuid:73e208b4-eb28-4e79-bb99-8b0b08b117e6
- Local pid:
-
pubs:117474
- Source identifiers:
-
117474
- Deposit date:
-
2012-12-19
Terms of use
- Copyright date:
- 2009
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