Conference icon

Conference

The role of corticotrophin-releasing hormone in the diagnosis of Cushing's syndrome

Abstract:

Background: Corticotrophin-releasing hormone (CRH) was identified by Vale and co-workers in 1981 and has since been used extensively in the diagnosis of ACTH-dependent Cushing's syndrome (CS). It was hoped that the CRH test would discriminate between pituitary and ectopic ACTH secretion. In adults, a rise from basal to peak plasma cortisol of ≥ 20% and ACTH of ≥ 50% is consistent with Cushing's disease (CD). Methods: Twenty-seven paediatric patients, with CD (mean age ± S.D. 13.1 ± 3.2; range...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1530/eje.1.02238

Authors


Volume:
155
Issue:
1
Pages:
S93-S98
Publication date:
2006-11-05
DOI:
EISSN:
1479-683X
ISSN:
0804-4643
URN:
uuid:7385101d-f1fe-4e0c-9fe7-f95092822c16
Source identifiers:
138573
Local pid:
pubs:138573

Terms of use


Metrics


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP