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Impact of human immunodeficiency virus type 1 subtypes on virologic response and emergence of drug resistance among children in the Paediatric European Network for Treatment of AIDS (PENTA) 5 trial.

Abstract:

The association between virologic response and human immunodeficiency virus type 1 (HIV-1) subtype was investigated in 113 HIV-1-infected children randomly assigned to receive zidovudine plus lamivudine, zidovudine plus abacavir, or lamivudine plus abacavir in the Paediatric European Network for Treatment of AIDS (PENTA) 5 trial. Symptomatic children (n=68) also received nelfinavir; asymptomatic children (n=45) were randomly assigned to receive nelfinavir or placebo. HIV-1 subtypes A, B, C, D...

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Publication status:
Published

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Publisher copy:
10.1086/342680

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Experimental Medicine Division,
Role:
Author
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Journal:
The Journal of infectious diseases
Volume:
186
Issue:
5
Pages:
617-625
Publication date:
2002-09-05
DOI:
EISSN:
1537-6613
ISSN:
0022-1899
URN:
uuid:73252ecf-3263-4a38-a83d-7ba84c7e7d75
Source identifiers:
423080
Local pid:
pubs:423080

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