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A molecular brake, not a clutch, stops the Rhodobacter sphaeroides flagellar motor

Abstract:

Many bacterial species swim by employing ion-driven molecular motors that power the rotation of helical filaments. Signals are transmitted to the motor from the external environment via the chemotaxis pathway. In bidirectional motors, the binding of phosphorylated CheY (CheY-P) to the motor is presumed to instigate conformational changes that result in a different rotor-stator interface, resulting in rotation in the alternative direction. Controlling when this switch occurs enables bacteria t...

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Publisher copy:
10.1073/pnas.0813164106

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Institution:
University of Oxford
Department:
Oxford, MPLS, Physics, REF-Physics
Role:
Author
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Journal:
Proceedings of the National Academy of Sciences of the United States of America
Volume:
106
Issue:
28
Pages:
11582-11587
Publication date:
2009-07-14
DOI:
EISSN:
1091-6490
ISSN:
0027-8424
URN:
uuid:7323cb83-cef0-4660-91a9-51161e733080
Source identifiers:
79821
Local pid:
pubs:79821
Language:
English

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