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Journal article

Spontaneous intermolecular amide bond formation between side chains for irreversible peptide targeting.

Abstract:

Peptides and synthetic peptide-like molecules are powerful tools for analysis and control of biological function. One major limitation of peptides is the instability of their interactions with biomolecules, because of the limited accessible surface area for noncovalent interactions and the intrinsic flexibility of peptides. Peptide tags are nonetheless fundamental for protein detection and purification, because their small size minimizes the perturbation to protein function. Here we have desi...

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Publication status:
Published

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Publisher copy:
10.1021/ja910795a

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Journal:
Journal of the American Chemical Society
Volume:
132
Issue:
13
Pages:
4526-4527
Publication date:
2010-04-05
DOI:
EISSN:
1520-5126
ISSN:
0002-7863
URN:
uuid:72de8c57-db51-478c-8bf9-19bc397468c1
Source identifiers:
101214
Local pid:
pubs:101214

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