Journal article

Safety and efficacy of whole-body chlorhexidine gluconate cleansing with or without emollient in hospitalised neonates (NeoCHG): a multicentre, randomised, open-label, factorial pilot trial

Abstract:: Background
Healthcare-associated infections account for substantial neonatal in-hospital mortality. Chlorhexidine gluconate (CHG) whole body skin application could reduce sepsis by lowering bacterial colonisation density, although safety and optimal application regimen is unclear. Emollients, including sunflower oil, may independently improve skin condition, thereby reducing sepsis. We aimed to inform which concentration and frequency of CHG, with or without emollient,... Expand abstract
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Publication status:: Published

Peer review status:: Peer reviewed

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APA Style

Russell, N., Clements, M. N., Azmery, K. S., Bekker, A., Bielicki, J., Dramowski, A., Ellis, S., Fataar, A., Hoque, M., LeBeau, K., O'Brien, S., Schiavone, F., Skoutari, P., Islam, M. S., Saha, S., Walker, A. S., Whitelaw, A., & Sharland, M. (2024). Safety and efficacy of whole-body chlorhexidine gluconate cleansing with or without emollient in hospitalised neonates (NeoCHG): a multicentre, randomised, open-label, factorial pilot trial. EClinicalMedicine, 69.

MLA Style

Russell, N., et al. “Safety and Efficacy of Whole-Body Chlorhexidine Gluconate Cleansing with or without Emollient in Hospitalised Neonates (NeoCHG): a Multicentre, Randomised, Open-Label, Factorial Pilot Trial.” EClinicalMedicine, vol. 69, Elsevier, 2024.

Chicago Style

Russell, N, MN Clements, KS Azmery, A Bekker, J Bielicki, A Dramowski, S Ellis, et al. 2024. “Safety and Efficacy of Whole-Body Chlorhexidine Gluconate Cleansing with or without Emollient in Hospitalised Neonates (NeoCHG): a Multicentre, Randomised, Open-Label, Factorial Pilot Trial.” EClinicalMedicine 69.
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Publisher copy:: 10.1016/j.eclinm.2024.102463

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+ Russell, N More by this author

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+ Clements, MN More by this author

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+ Azmery, KS More by this author

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+ Bekker, A More by this author

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+ Bielicki, J More by this author

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Bibliographic Details

Publisher:: Elsevier
Journal:: EClinicalMedicine More from this journal
Volume:: 69
Article number:: 102463
Publication date:: 2024-02-25
Acceptance date:: 2024-01-17
DOI:: 10.1016/j.eclinm.2024.102463
EISSN:: 2589-5370

Item Description

Language:: English
Keywords:: neonatal sepsis

infection prevention

antiseptic
Pubs id:: 1602508
Local pid:: pubs:1602508
Deposit date:: 2024-01-18

Terms of use

Copyright holder:: Russell et al
Copyright date:: 2024
Rights statement:: © 2024 The Authors. Published by Elsevier Ltd. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

Licence:: CC Attribution (CC BY)

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