Journal article
Alpha-tropomyosin mutations in inherited cardiomyopathies.
- Abstract:
-
The inherited cardiac diseases hypertrophic cardiomyopathy (HCM) and dilated cardiomyopathy (DCM) can both be caused by missense mutations in the TPM1 gene which encodes the thin filament regulatory protein α-tropomyosin. Different mutations are responsible for either HCM or DCM, suggesting that distinct changes in tropomyosin structure and function can lead to the different diseases. Various biophysical and physiological approaches have been used to investigate the structure-function effects...
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- Publication status:
- Published
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- Publisher copy:
- 10.1007/s10974-013-9358-5
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Bibliographic Details
- Journal:
- Journal of muscle research and cell motility
- Volume:
- 34
- Issue:
- 3-4
- Pages:
- 285-294
- Publication date:
- 2013-08-01
- DOI:
- EISSN:
-
1573-2657
- ISSN:
-
0142-4319
- Source identifiers:
-
421094
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:421094
- UUID:
-
uuid:7219e810-7aec-48d1-8398-7d945e90dffc
- Local pid:
- pubs:421094
- Deposit date:
- 2013-11-17
Terms of use
- Copyright date:
- 2013
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