Analysis of Brownian dynamics simulations of reversible biomolecular reactions

Journal article

A class of Brownian dynamics algorithms for stochastic reaction-diffusion models which include reversible bimolecular reactions is presented and analyzed. The method is a generalization of the λ-rho model for irreversible bimolecular reactions which was introduced in [11]. The formulae relating the experimentally measurable quantities (reaction rate constants and diffusion constants) with the algorithm parameters are derived. The probability of geminate recombination is also investigated.

Authors: Lipkova, J; Zygalakis, K; Chapman, S; Erban, R

• Publication date: 2010-01-01