Journal article
Optimal sampling designs for estimation of Plasmodium falciparum clearance rates in patients treated with artemisinin derivatives
- Abstract:
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BACKGROUND: The emergence of Plasmodium falciparum resistance to artemisinins in Southeast Asia threatens the control of malaria worldwide. The pharmacodynamic hallmark of artemisinin derivatives is rapid parasite clearance (a short parasite half-life), therefore, the in vivo phenotype of slow clearance defines the reduced susceptibility to the drug. Measurement of parasite counts every six hours during the first thre...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Preview, Version of record, pdf, 1.2MB, Terms of use)
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- Publisher copy:
- 10.1186/1475-2875-12-411
Authors
- Publisher:
- BioMed Central
- Journal:
- Malaria Journal More from this journal
- Volume:
- 12
- Article number:
- 411
- Publication date:
- 2013-11-13
- Acceptance date:
- 2013-10-28
- DOI:
- EISSN:
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1475-2875
- Language:
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English
- Keywords:
- Pubs id:
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438825
- UUID:
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uuid:71ad7427-f891-4804-9d47-07f706a40f90
- Local pid:
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pubs:438825
- Source identifiers:
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438825
- Deposit date:
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2013-12-12
- ARK identifier:
Terms of use
- Copyright holder:
- Flegg et al
- Copyright date:
- 2013
- Notes:
- © 2013 Flegg et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
- Licence:
- CC Attribution (CC BY)
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