Journal article icon

Journal article

Bromodomain-containing proteins in prostate cancer.

Abstract:

Several oncogenic factors have been involved in prostate cancer progression. However, therapeutic approaches still focus on suppression of androgen receptor (AR) signaling. In fact, whereas the full-length AR incorporates a ligand-binding domain, which has become a drug target for competitive inhibitors, other transcription factors often do not have tractable binding pockets that aid drug development. Consequently drug development efforts have turned to transcription co-regulators, often chro...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

Actions


Access Document


Publisher copy:
10.1016/j.mce.2017.06.007

Authors


More by this author
ORCID:
0000-0003-2931-3652
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Surgical Sciences
Oxford college:
Linacre College
ORCID:
0000-0001-5347-5083
South-East Norway Health Authorities More from this funder
Norwegian Centre for Molecular Medicine More from this funder
Southern and Eastern Norway Regional Health Authority More from this funder
Norwegian Research Council More from this funder
Expand funders...
Publisher:
Elsevier Publisher's website
Journal:
Molecular and cellular endocrinology Journal website
Publication date:
2017-06-05
Acceptance date:
2017-06-08
DOI:
EISSN:
1872-8057
ISSN:
0303-7207
Pubs id:
pubs:817467
URN:
uri:710b52a7-ef4a-4ffc-910e-7a22979e1441
UUID:
uuid:710b52a7-ef4a-4ffc-910e-7a22979e1441
Local pid:
pubs:817467

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP