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Journal article

Bromodomain-containing proteins in prostate cancer.

Abstract:

Several oncogenic factors have been involved in prostate cancer progression. However, therapeutic approaches still focus on suppression of androgen receptor (AR) signaling. In fact, whereas the full-length AR incorporates a ligand-binding domain, which has become a drug target for competitive inhibitors, other transcription factors often do not have tractable binding pockets that aid drug development. Consequently drug development efforts have turned to transcription co-regulators, often chro...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/j.mce.2017.06.007

Authors


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Role:
Author
ORCID:
0000-0003-2931-3652
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Institution:
University of Oxford
Division:
MSD
Department:
Surgical Sciences
Oxford college:
Linacre College
Role:
Author
ORCID:
0000-0001-5347-5083
Southern and Eastern Norway Regional Health Authority More from this funder
Norwegian Centre for Molecular Medicine More from this funder
South-East Norway Health Authorities More from this funder
Norwegian Research Council More from this funder
Norwegian Cancer Society More from this funder
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Publisher:
Elsevier Publisher's website
Journal:
Molecular and cellular endocrinology Journal website
Publication date:
2017-06-01
Acceptance date:
2017-06-08
DOI:
EISSN:
1872-8057
ISSN:
0303-7207
Pmid:
28624514
Source identifiers:
817467
Language:
English
Keywords:
Pubs id:
pubs:817467
UUID:
uuid:710b52a7-ef4a-4ffc-910e-7a22979e1441
Local pid:
pubs:817467
Deposit date:
2018-01-11

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