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Logistic proliferation of cells in scratch assays is delayed

Abstract:

Scratch assays are used to study how a population of cells re– colonises a vacant region on a two–dimensional substrate after a cell monolayer is scratched. These experiments are used in many applications including drug design for the treatment of cancer and chronic wounds. To provide insights into the mechanisms that drive scratch assays, solutions of continuum reaction–diffusion models have been calibrated to data from scratch assays. These models typically include a logistic source term to...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Accepted manuscript

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Publisher copy:
10.1007/s11538-017-0267-4

Authors


Pennington, CJ More by this author
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Department:
St Johns College
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Publisher:
Springer Verlag Publisher's website
Journal:
Bulletin of Mathematical Biology Journal website
Volume:
79
Issue:
5
Pages:
1028–1050
Publication date:
2017-03-23
Acceptance date:
2017-03-16
DOI:
EISSN:
1522-9602
ISSN:
0092-8240
Pubs id:
pubs:686274
URN:
uri:70ec07bc-eddb-45d0-835a-5259fbcef0fa
UUID:
uuid:70ec07bc-eddb-45d0-835a-5259fbcef0fa
Local pid:
pubs:686274

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