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Brain surface contraction mapped in first-episode schizophrenia: a longitudinal magnetic resonance imaging study.

Abstract:

Schizophrenia is associated with structural brain abnormalities, but the timing of onset and course of these changes remains unclear. Longitudinal magnetic resonance imaging (MRI) studies have demonstrated progressive brain volume decreases in patients around and after the onset of illness, although considerable discrepancies exist regarding which brain regions are affected. The anatomical pattern of these progressive changes in schizophrenia is largely unknown. In this study, MRI scans were ...

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Publication status:
Published

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Publisher copy:
10.1038/mp.2008.34

Authors


Stuart, GW More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neuroscience
McGorry, PD More by this author
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Journal:
Molecular psychiatry
Volume:
14
Issue:
10
Pages:
976-986
Publication date:
2009-10-05
DOI:
EISSN:
1476-5578
ISSN:
1359-4184
URN:
uuid:6ff92427-30a5-41a5-a87d-2a12407c717f
Source identifiers:
239224
Local pid:
pubs:239224

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