Journal article
Modern solutions for ancient pathogens: direct pathogen sequencing for diagnosis of lepromatous leprosy and cerebral coenurosis
- Abstract:
- Microbes unculturable in vitro remain diagnostically challenging, dependent historically on clinical findings, histology, or targeted molecular detection. We applied whole-genome sequencing directly from tissue to diagnose infections with mycobacteria (leprosy) and parasites (coenurosis). Direct pathogen DNA sequencing provides flexible solutions to diagnosis of difficult pathogens in diverse contexts.
- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Preview, Version of record, pdf, 507.2KB, Terms of use)
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- Publisher copy:
- 10.1093/ofid/ofac428
Authors
- Publisher:
- Oxford University Press
- Journal:
- Open Forum Infectious Diseases More from this journal
- Volume:
- 9
- Issue:
- 9
- Article number:
- ofac428
- Publication date:
- 2022-08-23
- Acceptance date:
- 2022-08-15
- DOI:
- EISSN:
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2328-8957
- Language:
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English
- Keywords:
- Pubs id:
-
1274223
- Local pid:
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pubs:1274223
- Deposit date:
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2022-08-15
Terms of use
- Copyright holder:
- Young et al.
- Copyright date:
- 2022
- Rights statement:
- © The Author(s) 2022. Published by Oxford University Press on behalf of Infectious Diseases Society of America. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (https://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact [email protected]
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