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Journal article

Clinically and microbiologically derived azithromycin susceptibility breakpoints for Salmonella enterica serovars Typhi and Paratyphi A.

Abstract:

Azithromycin is an effective treatment for uncomplicated infections with Salmonella enterica serovar Typhi and serovar Paratyphi A (enteric fever), but there are no clinically validated MIC and disk zone size interpretative guidelines. We studied individual patient data from three randomized controlled trials (RCTs) of antimicrobial treatment in enteric fever in Vietnam, with azithromycin used in one treatment arm, to determine the relationship between azithromycin treatment response and the ...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1128/aac.04729-14

Authors


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The Wellcome Trust More from this funder
University of Oxford-Li Ka Shing Global Health Foundation More from this funder
Publisher:
American Society of Microbiology Publisher's website
Journal:
Antimicrobial Agents and Chemotherapy Journal website
Volume:
59
Issue:
5
Pages:
2756-2764
Publication date:
2015-05-05
DOI:
EISSN:
1098-6596
ISSN:
0066-4804
URN:
uuid:6fbe72fb-0cd0-474b-84c9-868070083c65
Source identifiers:
509854
Local pid:
pubs:509854
Language:
English

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