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Journal article

The localisation and micro-mapping of copper and other trace elements in breast tumours using a synchrotron micro-XRF system.

Abstract:

Trace elements have critical roles in cancer biology. The quantity and distribution of the elements Cl, Ca, K, P, S, Ti, Fe, Cu and Zn in samples of primary breast cancer have been assessed. The samples were formalin fixed tissue specimens formatted as microarrays of cores 1.0 mm diameter and 10 microm thick each. The data were obtained using a synchrotron X-ray fluorescence microprobe system. The spatial resolution of elemental maps was approximately 20 microm. Maps were compared with light ...

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Publication status:
Published

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Authors


Farquharson, MJ More by this author
Falkenberg, G More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, Oncology, Biomedical Research Centre, Molecular Medicine
Journal:
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine
Volume:
65
Issue:
2
Pages:
183-188
Publication date:
2007-02-05
DOI:
EISSN:
1872-9800
ISSN:
0969-8043
URN:
uuid:6f8b7ada-eb6a-4532-a11a-72e5861b4926
Source identifiers:
125030
Local pid:
pubs:125030

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