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An expedient route to substituted furans via olefin cross-metathesis.

Abstract:

The olefin cross-metathesis (CM) reaction is used extensively in organic chemistry and represents a powerful method for the selective synthesis of differentially substituted alkene products. Surprisingly, efforts to integrate this remarkable process into strategies for aromatic and heteroaromatic construction have not been reported. Such structures represent key elements of the majority of small molecule drug compounds; methods for the controlled preparation of highly substituted derivatives ...

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Publication status:
Published

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Publisher copy:
10.1073/pnas.0913466107

Authors


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Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Organic Chemistry
Role:
Author
Journal:
Proceedings of the National Academy of Sciences of the United States of America More from this journal
Volume:
107
Issue:
8
Pages:
3373-3376
Publication date:
2010-02-01
DOI:
EISSN:
1091-6490
ISSN:
0027-8424
Language:
English
Keywords:
Pubs id:
pubs:48480
UUID:
uuid:6f504b87-4f06-43d4-b286-abde5f252796
Local pid:
pubs:48480
Source identifiers:
48480
Deposit date:
2012-12-19

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