- Abstract:
-
BACKGROUND: The efficacy of thiazolidinediones, as compared with other oral glucose-lowering medications, in maintaining long-term glycemic control in type 2 diabetes is not known. METHODS: We evaluated rosiglitazone, metformin, and glyburide as initial treatment for recently diagnosed type 2 diabetes in a double-blind, randomized, controlled clinical trial involving 4360 patients. The patients were treated for a median of 4.0 years. The primary outcome was the time to monotherapy failure, w...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1056/nejmoa066224
-
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- Journal:
- The New England journal of medicine
- Volume:
- 355
- Issue:
- 23
- Pages:
- 2427-2443
- Publication date:
- 2006-12-05
- DOI:
- EISSN:
-
1533-4406
- ISSN:
-
0028-4793
- URN:
-
uuid:6f42f8c3-b3e3-4eb6-98be-a060f66b24a9
- Source identifiers:
-
18100
- Local pid:
- pubs:18100
- Language:
- English
- Keywords:
- Copyright date:
- 2006
Journal article
Glycemic durability of rosiglitazone, metformin, or glyburide monotherapy.
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