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Journal article

Glycemic durability of rosiglitazone, metformin, or glyburide monotherapy.

Abstract:

BACKGROUND: The efficacy of thiazolidinediones, as compared with other oral glucose-lowering medications, in maintaining long-term glycemic control in type 2 diabetes is not known. METHODS: We evaluated rosiglitazone, metformin, and glyburide as initial treatment for recently diagnosed type 2 diabetes in a double-blind, randomized, controlled clinical trial involving 4360 patients. The patients were treated for a median of 4.0 years. The primary outcome was the time to monotherapy failure, w...

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Publication status:
Published

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Publisher copy:
10.1056/nejmoa066224

Authors


Haffner, SM More by this author
Herman, WH More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, RDM, OCDEM, Biomedical Research Centre
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Journal:
The New England journal of medicine
Volume:
355
Issue:
23
Pages:
2427-2443
Publication date:
2006-12-05
DOI:
EISSN:
1533-4406
ISSN:
0028-4793
URN:
uuid:6f42f8c3-b3e3-4eb6-98be-a060f66b24a9
Source identifiers:
18100
Local pid:
pubs:18100

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