Journal article
Expression of aberrant HLA-B27 molecules is dependent on B27 dosage and peptide supply.
- Abstract:
-
OBJECTIVES: Cellular expression of non-classical forms of human leukocyte antigen (HLA)-B27 (NC-B27) may be involved in spondyloarthritis (SpA) pathogenesis. We used a novel B27-specific monoclonal antibody, HD6, to ask if B27 transgenic (TG) rat splenocytes express these NC-B27 molecules. We also investigated whether B27-binding peptides could affect the expression and functional immune recognition of HD6-reactive B27 molecules. METHODS: Splenocytes from B27-TG, B7-TG and non-transgenic rats...
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- Publication status:
- Published
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- Publisher copy:
- 10.1136/annrheumdis-2012-203080
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Bibliographic Details
- Journal:
- Annals of the rheumatic diseases
- Volume:
- 73
- Issue:
- 4
- Pages:
- 763-770
- Publication date:
- 2014-04-01
- DOI:
- EISSN:
-
1468-2060
- ISSN:
-
0003-4967
- Source identifiers:
-
401838
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:401838
- UUID:
-
uuid:6f360593-5d4f-4289-8cee-597612aff3b3
- Local pid:
- pubs:401838
- Deposit date:
- 2013-11-16
Terms of use
- Copyright date:
- 2014
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