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Azithromycin resistance in Shigella spp. in Southeast Asia

Abstract:

Infection by Shigella spp. is a common cause of dysentery in Southeast Asia. Antimicrobials are thought to be beneficial for treatment, however antimicrobial resistance in Shigella spp. is becoming widespread. We aimed to assess the frequency and mechanisms associated with decreased susceptibility to azithromycin in Southeast Asian Shigella isolates and use these data to assess appropriate susceptibility breakpoints. Shigella isolated in Vietnam and Laos were screened for susceptibility again...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1128/aac.01748-17

Authors


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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDM; Tropical Medicine
Role:
Author
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Role:
Author
ORCID:
0000-0001-9189-7244
More from this funder
Name:
Royal Society
Funding agency for:
Baker, S
Grant:
Sir Henry Dale 365 Fellowship grant number 10008/Z/12/Z
Sir Henry Dale 365 Fellowship grant number 10008/Z/12/Z to SB
More from this funder
Name:
Wellcome Trust
Funding agency for:
Thwaites, G
Baker, S
Newton, P
Grant:
89276/2/09/2
Sir Henry Dale 365 Fellowship grant number 10008/Z/12/Z
106698/Z/14/ZtoDABD,PNN,RP
VD
106698/Z/14/Z
More from this funder
Name:
Oak Foundation
Grant:
B9R00910 to PTD
More from this funder
Name:
National Institutes for Health Research
Grant:
Academic Clinical 360 Lectureship grant number 3557 to TCD
More from this funder
Name:
Academy of Medical Sciences
Publisher:
American Society for Microbiology
Journal:
Antimicrobial Agents and Chemotherapy More from this journal
Volume:
62
Issue:
4
Pages:
e01748-17
Publication date:
2018-01-29
Acceptance date:
2017-11-02
DOI:
EISSN:
1098-6596
ISSN:
0066-4804
Pmid:
29378707
Language:
English
Keywords:
Pubs id:
pubs:822609
UUID:
uuid:6f1710fd-1f74-4104-be5b-c91a82106fe4
Local pid:
pubs:822609
Source identifiers:
822609
Deposit date:
2018-02-03

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