Journal article icon

Journal article

Raised intracranial pressure alters cortical vascular function and cephalic allodynia

Abstract:

Raised intracranial pressure (ICP) is associated with altered cerebral haemodynamics and cephalic pain. The relationship between the algetic response and cortical neurovascular changes in raised ICP is unclear. This study aimed to evaluate this relationship and determine whether lowering ICP (using a glucagon-like peptide-1 receptor agonist) could ameliorate the algetic response. We also sought to explore the role of calcitonin gene-related peptide in cephalic pain driven by raised ICP by inh...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

Actions


Access Document


Authors


More by this author
Role:
Author
ORCID:
0000-0001-5560-802X
More by this author
Role:
Author
ORCID:
0000-0002-2912-3632
More by this author
Institution:
University of Oxford
Role:
Author


More from this funder
Funder identifier:
https://ror.org/03x94j517
More from this funder
Funder identifier:
https://ror.org/0187kwz08
More from this funder
Funder identifier:
https://ror.org/029chgv08
More from this funder
Funder identifier:
https://ror.org/04q4ck618


Publisher:
Oxford University Press
Journal:
Brain More from this journal
Volume:
148
Issue:
6
Pages:
2163-2177
Publication date:
2025-03-08
Acceptance date:
2024-11-26
DOI:
EISSN:
1460-2156
ISSN:
0006-8950


Language:
English
Keywords:
Source identifiers:
2992497
Deposit date:
2025-06-03
This ORA record was generated from metadata provided by an external service. It has not been edited by the ORA Team.

Terms of use



Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP