Is lung function associated with bone mineral density? Results from the Hertfordshire Cohort Study.

Journal article

UNLABELLED: Given limited information available regarding associations between lung function and bone mineral density among healthy subjects, we undertook these analyses in the Hertfordshire Cohort Study. Forced expiratory volume in 1 s (FEV(1)), forced vital capacity (FVC) and FEV(1)/FVC were not associated with bone mineral density at any site; associations with bone mineral content were removed by adjustment for body size. PURPOSE: There is limited information available regarding the association between lung function and bone mineral density among healthy elderly subjects. We addressed this issue in the Hertfordshire Cohort Study. METHODS: From the above cohort, 985 subjects (496 men and 489 women) aged 60-72 years were recruited. All subjects underwent bone density measurements using dual energy X-ray absorptiometry and lung function tests using standardised spirometry. Chronic obstructive pulmonary disease (COPD) was defined as a FEV(1)/FVC ratio

Authors: Dennison, E; Dhanwal, D; Shaheen, S; Azagra, R; Reading, I

• Journal: Archives of osteoporosis
• Volume: 8
• Issue: 1-2
• Pages: 115
• Publication date: 2013-01-01
• DOI: 10.1007/s11657-012-0115-y
• EISSN: 1862-3514
• ISSN: 1862-3522
• Language: English
• Keywords: Aged; Spirometry; Humans; Cohort Studies; Female; Bone Density; Forced Expiratory Volume; Middle Aged; Pulmonary Disease, Chronic Obstructive; Lung; Absorptiometry, Photon; Male; Great Britain