- Abstract:
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Pre-eclampsia (PE) complicates around 3% of all pregnancies and is one of the most common causes of maternal mortality worldwide. The pathophysiology of PE remains unclear however its underlying cause originates from the placenta and manifests as raised blood pressure, proteinuria, vascular or systemic inflammation and hypercoagulation in the mother. Women who develop PE are also at significantly higher risk of subsequently developing cardiovascular (CV) disease. In PE, the failing endoplasmi...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Publisher's Version
- Files:
-
-
(pdf, 2.7MB)
-
- Publisher copy:
- 10.1371/journal.pone.0142538
-
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- Publisher:
- Public Library of Science Publisher's website
- Journal:
- PloS one Journal website
- Volume:
- 10
- Issue:
- 11
- Pages:
- e0142538
- Publication date:
- 2015-11-09
- Acceptance date:
- 2015-10-22
- DOI:
- ISSN:
-
1932-6203
- Pubs id:
-
pubs:579470
- URN:
-
uri:6e94ceca-a425-4314-87c9-c390d3248c29
- UUID:
-
uuid:6e94ceca-a425-4314-87c9-c390d3248c29
- Local pid:
- pubs:579470
- Language:
- English
- Keywords:
- Copyright holder:
- Tanetta et al.
- Copyright date:
- 2015
- Notes:
- © 2015 Tannetta et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited>
- License:
- CC BY
Journal article
Syncytiotrophoblast Extracellular Vesicles from Pre-Eclampsia Placentas Differentially Affect Platelet Function
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