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A new clade of insect-specific flaviviruses from Australian Anopheles mosquitoes displays species-specific host restriction.

Abstract:

Flaviviruses are arthropod-borne viruses found worldwide and are responsible for significant human and veterinary diseases, including dengue, Zika, and West Nile fever. Some flaviviruses are insect specific and replicate only in mosquitoes. We report a genetically divergent group of insect-specific flaviviruses from Anopheles mosquitoes that do not replicate in arthropod cell lines or heterologous Anopheles species, exhibiting unprecedented specialization for their host species. Determination...

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Publication status:
Published
Peer review status:
Peer reviewed

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Authors


Contributors

Role:
Editor
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Name:
Australian Infectious Diseases Research Centre
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Name:
Australian Research Council
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Name:
Western Australia Department of Health
Publisher:
American Society for Microbiology
Journal:
mSphere More from this journal
Volume:
2
Issue:
4
Pages:
e00262-17
Publication date:
2017-07-01
Acceptance date:
2017-06-13
DOI:
EISSN:
2379-5042
Language:
English
Keywords:
Pubs id:
pubs:709247
UUID:
uuid:6e288b85-c5db-41c1-955d-0cad7a077869
Local pid:
pubs:709247
Source identifiers:
709247
Deposit date:
2017-07-28

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