Journal article
Horseradish peroxidase-mediated gene therapy: choice of prodrugs in oxic and anoxic tumor conditions.
- Abstract:
-
We have previously proposed the plant enzyme horseradish peroxidase (HRP) and the plant hormone indole-3-acetic acid (IAA) as an enzyme/prodrug combination for cancer gene therapy. In the current study, we evaluated the potential of HRP/IAA for gene-directed enzyme/prodrug therapy in three human tumor cell lines (T24 bladder carcinoma, MCF-7 breast adenocarcinoma, and FaDu nasopharyngeal squamous carcinoma) and one endothelial cell line (HMEC-1). The action of 10 IAA analogues in combination ...
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Bibliographic Details
- Journal:
- Molecular cancer therapeutics
- Volume:
- 1
- Issue:
- 2
- Pages:
- 151-160
- Publication date:
- 2001-12-01
- EISSN:
-
1538-8514
- ISSN:
-
1535-7163
- Source identifiers:
-
255930
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:255930
- UUID:
-
uuid:6e137df5-790e-4ad4-afc5-d0b6ae4219d2
- Local pid:
- pubs:255930
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2001
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