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In vivo gene transfer into the testis by electroporation and viral infection--a novel way to study testis and sperm function.

Abstract:

The study of gene function in testis and sperm has been greatly assisted by creation of transgenic mice by injection of a transgene into the fertilised egg. However this approach is costly and laborious and is not applicable to other species of importance for the study of sperm function, such as the hamster. We have investigated alternative ways of expressing transgenes in mouse and hamster testis and sperm by in vivo gene transfer. DNA expression constructs were introduced into the testis by...

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Institution:
University of Oxford
Division:
MSD
Department:
Pharmacology
Role:
Author
Journal:
Society of Reproduction and Fertility supplement More from this journal
Volume:
65
Pages:
469-474
Publication date:
2007-01-01
ISSN:
1747-3403
Language:
English
Keywords:
Pubs id:
pubs:185350
UUID:
uuid:6e0baafc-6a8e-471d-b872-a5a654a939b4
Local pid:
pubs:185350
Source identifiers:
185350
Deposit date:
2012-12-19

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