Journal article
Polymorphisms in Pvkelch12 and gene amplification of Pvplasmepsin4 in plasmodium vivax from Thailand, Lao PDR and Cambodia
- Abstract:
-
Background Mutations in Pfkelch13 and Pfplasmepsin2/3 gene amplification are well-established markers for artemisinin and piperaquine resistance in Plasmodium falciparum, a widespread problem in the Greater Mekong Subregion (GMS). The Plasmodium vivax parasite population has experienced varying drug pressure dependent on local drug policies. We investigated the correlation between drug pressure from artemisinins and piperaquine and mutations in the P. vivax orthologous genes Pvkelch12 and Pvp...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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Authors
Bibliographic Details
- Publisher:
- BioMed Central Publisher's website
- Journal:
- Malaria Journal Journal website
- Volume:
- 18
- Article number:
- 114
- Publication date:
- 2019-04-02
- Acceptance date:
- 2019-03-26
- DOI:
- ISSN:
-
1475-2875
Item Description
Terms of use
- Copyright holder:
- Duanguppama et al
- Copyright date:
- 2019
- Notes:
- © The Author(s) 2019. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
- Licence:
- CC Attribution (CC BY)
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