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Effect of a quadrivalent meningococcal ACWY glycoconjugate or a serogroup B meningococcal vaccine on meningococcal carriage: an observer-blind, phase 3 randomised clinical trial.

Abstract:

BACKGROUND: Meningococcal conjugate vaccines protect individuals directly, but can also confer herd protection by interrupting carriage transmission. We assessed the effects of meningococcal quadrivalent glycoconjugate (MenACWY-CRM) or serogroup B (4CMenB) vaccination on meningococcal carriage rates in 18-24-year-olds. METHODS: In this phase 3, observer-blind, randomised controlled trial, university students aged 18-24 years from ten sites in England were randomly assigned (1:1:1, block size ...

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Publication status:
Published

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Journal:
Lancet More from this journal
Volume:
384
Issue:
9960
Pages:
2123-2131
Publication date:
2014-12-01
DOI:
EISSN:
1474-547X
ISSN:
0140-6736
Language:
English
Pubs id:
pubs:481012
UUID:
uuid:6ddfc88e-9ab0-4115-a132-ee9e2c91cb08
Local pid:
pubs:481012
Source identifiers:
481012
Deposit date:
2014-08-30

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